Peaches 'N Cream is recruited by Cheryl to create the family Toni lost after being kicked out the Southside Serpents. Toni is extremely grateful, referring to Cheryl’s gesture as the most bad ass and romantic thing she’s ever done. Peaches 'N Cream inquiries about the name for their newly found family, to which Toni falls on the name "Pretty Poisons." Pretty by day, poison by night.
Just outside Thistlehouse, Cheryl teaches an archery class to Peaches and the other Pretty Poisons girls. Toni returns not long after to inform Cheryl how Jughead attempted to convince her to rejoin the Serpents, which triggers Cheryl and causes her to react. Led by Cheryl, the Pretty Poisons confront Sweet Pea and Fangs as they are leaving Pop's Chock'lit Shoppe. Sweet Pea sarcastically remarks that that he and Fangs don’t want any trouble from their sorority. Cheryl demands respect, to which Fangs questions the consequence of should they not. Cheryl explains who they are and why they’re there. They’ve come to deliver a message to the Serpents, that they’re not to be dismissed or trifled with. The ladies proceed to surround and attack Sweet Pea and Fangs, who choose not to defend themselves.
Evelyn, Kevin, and the rest of the young Farmies enter their reserved classroom for the Farm meeting only to find Kurtz and the other Gargoyles turned Serpents occupying the classroom while playing Gryphons and Gargoyles. Just as Evelyn informs them that they have rights to the class every Wednesday, Cheryl, Peaches 'N Cream and the rest of the Pretty Poisons interject to lay their claim to the room. Cheryl explains that the third Wednesday of every month is reserved for monthly student council/LGBTQIA meetings. Evelyn questions the validity of Cheryl’s claims, to which Cheryl replies that she would have Evelyn beheaded in another century. It’s only when Kurtz refers to the ladies as "bitches" that the altercation turns violent, forcing Jughead and Toni to intervene.
The Pretty Poisons are hired as security to La Bonne Nuit by Veronica. Gladys arrives at Pop’s with intentions on heading downstairs to La Bonne Nuit though her entry is blocked by Peaches ‘N Cream, Toni, and the Pretty Poisons. Under new house rules, Gladys is no longer permitted into La Bonne Nuit without an engraved invitation. Gladys doubts they can stop her, but Veronica joins the girls and tells Gladys to step off. She hired the girls to block her admittance until Gladys learns to play by Veronica’s rules. Her father then enters the diner, hoping that Veronica saved for him his favorite booth. However, Hiram isn’t permitted into La Bonne Nuit either, at least not until he starts to show Veronica proper respect. She also warns him not to flex his financial hold over her. She’ll pay him back as they agreed. But, moving forward, she’s running her business, her way.
Peaches, Toni and the Poisons arrive at school during Cheryl's musical number, though they don't speak in passing. Peaches then joins Archie, Kevin, Cheryl, Veronica, Betty, Reggie, Sweet Pea, Fangs, Josie, and Evelyn the hall in song and dance. They then make their way to the auditorium and get on stage, where they conclude their performance.
Peaches, Archie, Betty, Veronica, Cheryl, Toni, Josie, Sweet Pea, Fangs, and Reggie lay on their backs in the student lounge as Evelyn tells them that everything in their lives matter. There are universal truths within each of their experiences. In rehearsal, they’re going to explore their own personal traumas and experiences and exercise them through their art. Kevin interrupts to inform Cheryl, Veronica, and Betty that "Candy Store" set and costumes are ready.
Once in the auditorium, Kevin explains to Cheryl, Veronica, and Betty that this number is about the Heathers undeniable power that each of them can get at any given time. Peaches, Toni, and the Poisons are also on stage. Toni, as choreographer, wants to start with some simple steps, but Cheryl, still upset over their breakup, doesn’t want to hear it, telling both Toni and Kevin that she, Betty, and Veronica have already worked out their own choreography. Toni’s attempt at being professional is undermined by Cheryl, who along with Betty and Veronica, begin their musical number. Peaches, Toni, and the Poisons join in on the number, which upsets Cheryl, leading to a showdown between the two, who go back and forth on stage. Cheryl stops in the middle of their performance to tell Toni to shut up, though Toni persists, and so Cheryl shoves her and concludes the song.
The cast meets up at the Sisters of Quiet Mercy compound as planned. It isn't long before Peaches 'N Cream, Toni, and the Pretty Poisons join in, which upsets Cheryl, as she was hoping that Toni wouldn’t come.
Peaches and Sweet Pea are approached by Toni, who seeks to hookup with them both after a confrontation with Cheryl. She takes them to the auditorium and tells them to get undressed. Unbeknownst to Toni, Cheryl sits off by the window. She decides to join in on the song. Toni caves at the last moment and tells both Sweet Pea and Peaches who are nearly naked that she’s sorry as she can’t go through with it.
Peaches 'N Cream attends a meeting called by Betty and Jughead between the Serpents and Pretty Poisons, with whom he has a proposition for. Peaches 'N Cream states that they don’t take orders from Jughead, though Betty pleads with her to make a prom night truce so that they can all work together to catch the Gargoyle King. During prom, groups of them will be stationed at every entrance. Once the announcement for Prom Queen begins, they’re going to keep everyone from exiting the gym. The Gargoyle King will be there, and this is their one chance at getting him, though they don’t know if he’ll be in costume or not. At the minimum, he will have some kind of kingly signifier, like a crown or antlers. He’s going to make his move after Betty is crowned Prom Queen. The Serpents and Poisons then come together as one.
Prom has finally started. Betty and Jughead arrive not long after. Peaches 'N Cream asks if they want to run for Prom court. Betty has been running unopposed. As an extra measure, Betty has cooked up dozens of fake votes, which Peaches proceeds to add to the count. With the Serpent and Poisons in place, Betty and Jughead now have to wait for him to make his move. Later, Peaches, Jughead, Archie, Veronica, Kevin, Fangs, Evelyn, Cheryl, and Toni stand in the crowd as Betty is announced as the Prom Queen, though no one seems to know where she is.
At La Bonne Nuit, bets are being placed, with Peaches 'N Cream working the operation. Just moments after Peaches gets a call from one of the spectators at the fight, the FBI raids the speakeasy.
Just outside Thistlehouse, Toni has rallied the Pretty Poisons and Southside Serpents in preparation to storm the Farm and retrieve Cheryl. Much to their surprise, Cheryl has already escaped. She joins them, handing Juniper off Peaches 'N Cream, who hands her off to Nana Rose. Cheryl runs into Toni’s arms and they kiss. Cheryl asks where is Betty. Nana Rose replies that she’s being hunted at Thronhill with all the others. Penelope has been planning this for weeks. It’s the grand hunt. With little time to spare, the Poisons and Serpents ride out.
The Pretty Poisons and Serpents, led by Toni and Cheryl, begin firing arrows at the Gargoyles as they chase down Archie, Betty, Veronica, and Jughead. As they begin to retreat, the Poisons and Serpents charge forward.
Fred’s funeral is held. Peaches, Cheryl, Toni, Nana Rose, Betty, Archie, Veronica, Jughead, Mary, FP, Pop, Josie, Kevin, Tom, Sierra, are in attendance, along with many others. Josie sings "Amazing Grace" as Archie, Jughead, Reggie, Kevin, FP, and Tom carry the casket. After the town pays their respect, Archie says a few words, ending with Fred Andrews will always be a part of Riverdale.
Peaches 'N Cream DJs Cheryl and Toni's back-to-school party at Thistlehouse. Archie, Jughead, Betty, Veronica, Mad Dog, and Reggie are in attendance. Cheryl declares Mr. Honey as their latest enemy. She assures the student body that he’ll be taken care of by Homecoming. Sheriff Jones pulls up and brings an end to the party after receiving a noise complaint from Mr. Honey.
Peaches is a young woman who dresses in dark clothing.